The US Senate on Thursday confirmed Jennifer Granholm as secretary of energy, the first of President Joe Biden’s nominees for key cabinet portfolios who will help lead his administration’s ambitious clean energy and climate strategy over the next four years.

The vote was 64-35 with all 48 Democrats and two independents who caucus with them plus 14 opposition Republicans voting yes. Some Republicans who opposed her nomination represent western states that heavily depend on royalties and tax revenues from extraction of fossil fuels to balance their budgets and fund public education.